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Measuring it: biological age

Before anything can be called age reversal, it has to be measured. Aging clocks estimate how old your body seems from blood tests or chemical tags on your DNA.

Compare biological age tests → · What is biological age? → · What is an epigenetic clock? →

Biological age tests

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Recent research

Study in Genetic data plus a large US health survey of postmenopausal women · Biology of sex differences

Hormone replacement therapy and survival, linked to aging clocks and blood sugar

This study linked estrogen signals and hormone therapy to slower aging clock markers and lower death risk.

Original title: Hormone replacement therapy through the lens of epigenetic clock: estrogen signals, glycemic status, and lifespan.
New trial · ClinicalTrials.gov

Testing whether medicines and a skin treatment can lower biological age

This study is a trial that is still signing up people by invitation, and no results have been posted yet.

Original title: Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks
Early results in Several groups of adults in studies that watched people over time, 7,469 in the main follow-up group · medRxiv

Urine test linked to aging may predict death and heart disease risk

A urine-based aging score was linked to higher risk of death and some heart and kidney problems.

Original title: A kidney-conditioned urinary peptidomic biological ageing clock predicts all-cause mortality and age-related health outcomes
Study in 13,174 adults in Great Britain, with 3,636 in the DNA test group · European journal of ageing

Living in poorer areas linked to faster aging and worse health in Britain

People in more deprived areas showed faster biological aging, weaker thinking skills, and worse self-rated health.

Original title: Area deprivation and multi-domain measures of ageing: biological ageing, cognitive, and subjective health across the entire adult age span.
Study in 890 adults aged 20 to 102 · GeroScience

How activity, sitting, and sleep relate to biological aging clocks

This study looked at how movement, sitting time, and sleep quality link to measures of aging in the body.

Original title: Physical activity, sedentary behavior, sleep quality and the biological aging clocks.
Early results in 401 Finnish twins, average age 62, followed about 10 years; early results not yet checked by other scientists · medRxiv

Protein-based aging clocks and cancer risk in Finnish twins

Some protein aging scores linked to death from any cause.

Original title: Systemic and organ-specific proteomic aging clocks as predictors of cancer incidence and survival: insights from the Finnish Twin Cohort
Study in 9,410 middle-aged and older adults in China · Journal of Alzheimer's disease reports

Lower biological age linked to fewer mild thinking problems in older Chinese adults

Researchers tracked people over time to see if a biological age score predicted mild memory and thinking problems.

Original title: Association between Gompertz law-based biological age (GOLD BioAge) and incident mild cognitive impairment: Modifying role of social activeness.
New trial · ClinicalTrials.gov

Study checks if a blood-based aging test predicts IVF success

Researchers planned to compare a blood measure of biological age in women who did and did not have a live birth after IVF.

Original title: Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART

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This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.