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Testing whether medicines and a skin treatment can lower biological age

Enrolling by invitation · EARLY PHASE 1 · Frontiers in Bioscience Research Institute and Aging

What this means

This study is a trial that is still signing up people by invitation, and no results have been posted yet. It will test whether treatments can lower measured biological age in skin and blood.

Plain-English summary written by an AI model from the registry listing.

Status
Enrolling by invitation
Who can join
Ages 50–100
Where
1 site, including California

Contacts and how to join ↗

The science

Registered title
Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks
Phase
EARLY PHASE 1
Study type
interventional
Conditions
Aging
What is tested
Topical anti-aging peptide serum
Sponsor
Frontiers in Bioscience Research Institute and Aging
Ages
50 Years to 100 Years
Dates
First posted Oct 22, 2026 · updated Oct 22, 2026

Registry summary

This study tests whether certain medicines and a skin treatment can slow down or partly reverse the body's aging process.

As people age, the activity of their genes changes in predictable ways. Researchers can now measure a person's "biological age" from these gene-activity patterns in skin and blood. This study uses that measurement to see whether treatment can lower a person's biological age compared with their own starting point.

Adults in the study take geroprotective ("age-protecting") agents by mouth or by injection. A separate skin serum containing small anti-aging peptides is applied to certain areas of skin, and those treated areas are compared with untreated areas on the same person.

Skin and blood samples are taken at set times to measure biological age and markers of cell aging before, during, and after treatment. The main goal is to find out whether treatment lowers measured biological age in skin and blood. The study also looks at whether the treatments are safe and well tolerated.

Sites (1)

  • Frontiers in Bioscience Research Institute in Aging and Cancer, Irvine, California, United States

Related treatments

Metformin · Urolithin A · Collagen peptides

More aging trials in these states

California

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