Can an AI-chosen skincare routine help aging skin in women 35 to 65?
This study will test whether a skincare plan picked by an AI tool improves fine lines, wrinkles, and skin tone. It does not yet show whether the plan works, since no results have been posted.
Original title: AI-Personalized Skincare Regimen for Facial Photoaging in Women
A planned study of exercise and fitness in older adults in China
This study plans to follow about 8,960 adults aged 60 to 79 over time. It has not started recruiting, so no results exist yet.
Original title: China Healthy Aging and Fitness Longitudinal Study
Chicken essence drink tested for effects on biological age
This is a trial registration, so it describes a planned study. It does not show whether the drink changes biological age.
Original title: Biological Age Study of Chicken Essence
A planned trial of trigonelline supplements in healthy adults aged 40 to 70
This trial plans to test four doses of a supplement against a placebo and a similar supplement, NMN. It has not started yet and has no results, so it cannot yet show whether the supplement works.
Original title: Effects of Trigonelline Monohydrate on NAD+ Metabolism, Pharmacokinetics, Safety, and Tolerability in Healthy Adults
Looking at patient records for drooling and a botulinum toxin treatment
Researchers will search old clinic records for adults with chronic drooling who were given incobotulinumtoxinA shots. This is a record review, so it will show how often the treatment is used, not whether it works.
Original title: A Retrospective Chart Abstraction to Investigate the Prevalence of Chronic Sialorrhea, and the Real-world Use of incobotulinumtoxinA Injections in Male and Female Participants Aged 18 Years and Older With Chronic Sialorrhea
Checking Uzbek versions of three men's health questionnaires
Researchers plan to test whether three questionnaires work well in Uzbek for men aged 35 to 59. The study has not reported results, so it does not yet show whether they are reliable.
Original title: Validation of Uzbek-Language ADAM, AMS, and IPSS Questionnaires in Men Aged 35-59 Years
A phone peer support study for older adults with serious mental illness
This study plans to test a 12-week phone program that helps older adults manage their health and daily life. It has not started recruiting, and no results have been posted yet.
Original title: Supporting Older Adults Remotely
Small pilot tests drug and digital tracking for healthy aging in older adults
A small study gave 31 adults in Israel one of two drug mixes for about eight weeks and tracked them with phone-based checks. The study did not report results yet, so it cannot tell us whether either approach helps.
Original title: ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy Aging
Study checks if a blood-based aging test predicts IVF success
Researchers planned to compare a blood measure of biological age in women who did and did not have a live birth after IVF. This registration has no results yet, so it does not tell us whether the test predicts success.
Original title: Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART
Study compares muscle tiredness in younger and older adults and tests strength training
Researchers plan to compare younger and older adults to learn why leg muscles tire faster with age. They also plan to test an 8 week strength program, with and without blood flow restriction, in older adults.
Original title: Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
A planned trial will test fisetin, a natural compound, in older adults
This trial plans to test whether fisetin, a natural compound, can improve blood vessel function in older adults. It also plans to check safety, and whether people keep taking it, but it has not started and has no results yet.
Original title: Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial
Can light weight training with blood flow limits help colon cancer survivors with muscle loss?
This is a trial plan that has not reported results yet. It will test whether the training improves strength, daily movement, and tiredness.
Original title: Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia
A filler device for facial wrinkles is being tested in 43 adults
This study plans to check how well a gel device works for facial wrinkles and whether it is safe. The study has not reported any results yet, so it cannot show whether the device works.
Original title: Evaluation of the Performance and Safety of the MD60000 Device in the Treatment of Skin Imperfections Due to Aging.
Testing whether a switch to doravirine/islatravir changes aging markers in people with HIV
This is a planned study that has not started enrolling people yet, so no results exist. It will not tell us anything about aging effects until it runs and reports.
Original title: Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV
Testing balance and walking after a 4-week AI-guided exercise program
This study plans to check balance, walking, and brain activity before and after 4 weeks of exercise. It has not reported results, so it cannot yet show whether the program helps.
Original title: Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
Testing a traditional Chinese exercise against resistance training for muscle loss
This is a plan for a study, and it has not started recruiting people yet. It does not tell us yet whether the exercise works, because no results have been posted.
Original title: Yijinjing Exercise for Musculoskeletal Health in Adults With Sarcopenia