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Dan Promislow at ARDD2026: The Companion Dog as a Translational Model of Aging

ARDD · Oct 26, 2026

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What this video covers

A video from ARDD, posted on Oct 26, 2026. It is about measuring biological age, drugs tested against aging and the science of aging. It names Rapamycin.

It comes from a research institute, foundation or scientific meeting on aging. We link to it; we don't make or endorse it. Research stages on this site come from published studies, not from videos.

From the video's description

Dan Promislow, HNRCA at Tufts University, presents at the 13th Aging Research and Drug Discovery Meeting: The Companion Dog as a Translational Model of Aging Key takeaways: – More than 55,000 dogs enrolled since 2020; a Precision Cohort of ~1,000 dogs gives annual biospecimens; data shared via the Broad's Terra. – NIA renewed funding for five more years; a new cohort of ~1,000 of the oldest U.S. dogs will get 30x genomes; the Precision Cohort could grow to 3,000 and add transcriptome, proteome and lipidome with more support. – Dogs with lower epigenetic age live longer; genes hypomethylated with age in dogs tend to rise in expression in aging humans. – 25 metabolites (enriched for kidney markers) predict mortality in dogs and in the same direction in humans, found with 2.6 years of follow-up vs. 8–25 in human studies. – GWAS linked a chromosome 25 SNP to kynurenic acid; coat "furnishing…

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