What this means
The goal of this clinical trial is to learn whether taking a daily supplement of β-hydroxy-β-methylbutyrate (HMB) while following a structured exercise program improves body composition, muscle strength and physical performance in older women. The main question it aims to answer is: does HMB (3 g per day) combined with the Vivifrail multicomponent exercise program improve handgrip strength more than the same exercise program combined with maltodextrin without HMB?
A plain-English summary is on its way. Until then, this is the start of the registry's own summary.
- Status
- Opening soon
- Who can join
- Ages 60–80
- Where
- 1 site
The science
- Registered title
- Effect of HMB Supplementation and Vivifrail Exercise on Body Composition, Handgrip Strength and Physical Performance in Women Over 60 Years of Age
- Trial ID
- NCT07905755 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging, Muscle Strength, Physical Functional Performance, Body Composition
- What is tested
- Calcium β-hydroxy-β-methylbutyrate (HMB-Ca), Maltodextrin (Placebo), Vivifrail multicomponent exercise program
- Sponsor
- Universidad Autónoma del Estado de Hidalgo
- Ages
- 60 Years to 80 Years
- Dates
- First posted Oct 29, 2026 · updated Oct 29, 2026
Registry summary
The goal of this clinical trial is to learn whether taking a daily supplement of β-hydroxy-β-methylbutyrate (HMB) while following a structured exercise program improves body composition, muscle strength and physical performance in older women. The main question it aims to answer is: does HMB (3 g per day) combined with the Vivifrail multicomponent exercise program improve handgrip strength more than the same exercise program combined with maltodextrin without HMB? Researchers will also compare body composition and physical performance between groups.
Participants will take the assigned supplement every day for 12 weeks, attend three supervised Vivifrail exercise sessions per week at the Casa Club de la Tercera Edad (DIF Tulancingo, Hidalgo, Mexico), and complete evaluations at baseline, week 6 and week 12.
Sites (1)
- Casa Club de la Tercera Edad, Sistema DIF Tulancingo, Tulancingo, Hidalgo, Mexico