What this means
This study will investigate how communication between the cerebellum and cerebral cortex contributes to balance control and adaptation in younger and older adults. The study will enroll healthy younger adults ages 21-35 years and older adults ages 65-95 years.
A plain-English summary is on its way. Until then, this is the start of the registry's own summary.
- Status
- Opening soon
- Who can join
- Ages 21–95
- Where
- 1 site, including Minnesota
The science
- Registered title
- Cerebello-Cortical Connectivity and Balance Adaptation in Younger and Older Adults
- Trial ID
- NCT07901322 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging, Postural Balance, Motor Adaptation
- What is tested
- Transcranial Magnetic Stimulation Assessment, Reactive Balance Adaptation Task
- Sponsor
- University of Minnesota
- Ages
- 21 Years to 95 Years
- Dates
- First posted Oct 28, 2026 · updated Oct 28, 2026
Registry summary
This study will investigate how communication between the cerebellum and cerebral cortex contributes to balance control and adaptation in younger and older adults.
The study will enroll healthy younger adults ages 21-35 years and older adults ages 65-95 years. Participants will complete a single testing session that includes clinical balance assessments, transcranial magnetic stimulation (TMS), electroencephalography (EEG), electromyography (EMG), and reactive balance testing using an instrumented treadmill.
Cerebello-cortical connectivity will be measured before and after reactive balance testing using cerebellar brain inhibition (CBI) and the cerebellar TMS-evoked potential P80. The study will examine how these measures relate to cortical activity, balance recovery, and adaptation across repeated perturbations, and whether these relationships differ between younger and older adults.
Sites (1)
- University of Minnesota - Brains in Motion Laboratory, 426 Church Street SE, Room 219, Children's Rehabilitation Center, Minneapolis, Minnesota, United States