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Does exercise before colorectal cancer surgery lower complications? A new trial is recruiting

Recruiting · Semmelweis University

What this means

This trial is testing whether strength, endurance, or both kinds of exercise before surgery lower complications. It has not reported results yet, so it cannot yet show if any exercise helps.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 18 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
Phase
Not applicable
Study type
interventional
Conditions
Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
What is tested
Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
Sponsor
Semmelweis University
Ages
18 Years to no maximum
Dates
First posted Oct 26, 2026 · updated Oct 26, 2026

Registry summary

The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions. The main questions it aims to answer are:

  • Does resistance (strength) training, aerobic (endurance) training, or a combination of both before surgery lower the rate and severity of complications in the first 30 days after surgery, compared with no exercise program?
  • Which factors influence how well patients follow a prehabilitation program, and does following the program affect surgical outcomes?

Researchers will compare three exercise groups with a control group that receives standard care without an exercise program.

Participants will:

  • Be randomly assigned to one of four groups: resistance training, aerobic training, combined training, or no exercise program (control)
  • Do the assigned home exercise program for 4 to 6 weeks before surgery, with weekly physiotherapy check-ups in person or by phone
  • Receive nutritional counseling, breathing exercises, and psychological support if needed, regardless of group
  • Keep a daily exercise diary and record their pulse daily
  • Undergo physical fitness tests (walking test, sit-to-stand test, handgrip strength) and quality-of-life questionnaires before surgery and 8 weeks after surgery

Sites (1)

  • Semmelweis University, Department of Surgery, Transplantation and Gastroenterology, Budapest, Hungary

Related treatments

Exercise · Strength training

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