What this means
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water. The study will include 38 participants who habitually consume 35 mL/kg/day or less of water.
A plain-English summary is on its way. Until then, this is the start of the registry's own summary.
- Status
- Opening soon
- Who can join
- Ages 60–85
- Where
- Not listed
The science
- Registered title
- Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
- Trial ID
- NCT07892742 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
- What is tested
- Water
- Sponsor
- Polytechnic University of Santarém
- Ages
- 60 Years to 85 Years
- Dates
- First posted Oct 23, 2026 · updated Oct 23, 2026
Registry summary
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
The study will include 38 participants who habitually consume 35 mL/kg/day or less of water. Participants will be randomly assigned to either increase their daily water intake to at least 45 mL/kg/day or maintain their usual water intake for 7 days.
Before and after the 7-day intervention, participants will undergo assessments of hydration, blood and urine markers, hormone levels, body water distribution, body composition, muscle and physical function, mood, physical activity, and health-related quality of life.
The main purpose of the study is to determine whether increasing habitual water intake changes levels of arginine vasopressin, a hormone involved in the regulation of body water balance. The study will also investigate whether increasing water intake is associated with changes in hydration status, cardiovascular and kidney-related markers, stress-related hormones, body water distribution, physical performance, mood, and quality of life.
The results may help clarify whether increasing habitual water intake is a feasible strategy to improve hydration and support healthy ageing in older adults who habitually drink relatively little water.