What this means
This trial plans to test whether a ketone drink with protein after resistance exercise changes how the body breaks down and uses protein. It has not started, so no results exist yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 65 and over
- Where
- Not listed
The science
- Registered title
- Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males
- Trial ID
- NCT07884513 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Ketosis, Resistance Exercise, Dietary Protein, Aging, Anabolic Resistance, Post-exercise Period
- What is tested
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Sponsor
- McGill University
- Ages
- 65 Years to no maximum
- Dates
- First posted Oct 20, 2026 · updated Oct 20, 2026
Registry summary
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in older trained males. This trial will compare the difference in phenylalanine metabolism between the ketone monoester and control conditions. Secondary outcomes including plasma amino acid, plasma insulin, plasma glucose, capillary blood beta-hydroxybutyrate concentrations and whole body myofibrillar protein breakdown rate (k) will be explored as secondary measures. Ketone monoester supplementation with protein in the post-resistance exercise period will be compared to the control condition of just protein in the post-resistance exercise period.