What this means
The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation in the treatment of patients aged 17 to 65 years with symptomatic articular chondral or osteochondral defects of the talus.
A plain-English summary is on its way. Until then, this is the start of the registry's own summary.
- Status
- Recruiting
- Who can join
- Ages 17–65
- Where
- 9 sites, including California, District of Columbia, Kansas
The science
- Registered title
- A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle
- Trial ID
- NCT06915233 ↗
- Phase
- PHASE 3
- Study type
- interventional
- Conditions
- Chondral Defect, Articular Cartilage Defect
- What is tested
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Sponsor
- Vericel Corporation
- Ages
- 17 Years to 65 Years
- Dates
- First posted Apr 8, 2025 · updated Oct 26, 2026
Registry summary
The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation in the treatment of patients aged 17 to 65 years with symptomatic articular chondral or osteochondral defects of the talus.
Sites (9)
- UC Davis Foot and Ankle Clinic, Sacramento, California, United States
- MedStar Georgetown University Hospital, Washington D.C., District of Columbia, United States
- Elevate Clinical Research Wichita, Wichita, Kansas, United States
- Mayo Clinic, Rochester, Minnesota, United States
- Duke Orthopaedic Surgery, Durham, North Carolina, United States
- University of Pittsburgh Medical Center Freddie Fu Sports Medicine Center, Pittsburgh, Pennsylvania, United States
- Elevate Clinical Research, Houston, Texas, United States
- Rodaro, LLC, San Antonio, Texas, United States
- UVA Orthopedic Center Ivy Road, Charlottesville, Virginia, United States
Related treatments
More aging trials in these states
California · District of Columbia · Kansas · Minnesota · North Carolina · Pennsylvania · Texas · Virginia