Investigating the efficacy and toxicity of partial in vivo reprogramming as a rejuvenation intervention.
Partial reprogramming by cyclic expression of Yamanaka factors has been proposed as a rejuvenation strategy, yet evaluating tissue-specific responses and potential risks remains challenging.
Partial reprogramming in aged mice reduced brain damage after a stroke-like event
Researchers turned on four reprogramming genes in older mice and then blocked a brain artery. Those mice had smaller brain damage and better movement than normal mice.
A new idea about how body-wide signals may speed up aging late in life
This paper proposes a theory that signals between cells across the body shape how fast aging speeds up. It is an idea, not a tested result, so it does not prove the theory is right.
Plant extracts studied for effects on aging skin cells in a preprint
Researchers tested plant extract mixes on aged skin cells and skin samples in a lab. This is an early preprint, not yet checked by other scientists, so it does not show these mixes help real skin.
Gene SRSF1 slowed signs of aging in cells and in older mice
Scientists boosted one gene in aged human cells and in mice. It made the cells and mice look younger in some ways. This does not show it would work the same way in people.