How people get it: At pharmacies and doctors' offices. In the US, recommended vaccines are usually covered by insurance.
The basics
What it is
Vaccinations are also known as shots or immunizations. An adjuvant is an extra ingredient in some flu vaccines that helps create a stronger immune response.
Source: National Institute on Aging: Vaccinations and Older Adults ↗
How it's thought to help
Flu vaccines make the body develop antibodies about two weeks after the shot. These antibodies protect against flu illness.
Source: CDC: Key Facts About Seasonal Flu Vaccine | Influenza (Flu) ↗
What people use it for
Travel vaccines are used depending on where a person is going, what they plan to do, and their medical history.
Source: National Institute on Aging: Vaccinations and Older Adults ↗
What the research has found so far
A 2021 study found flu vaccination was linked to a 26% lower risk of ICU admission and a 31% lower risk of death from flu among adults. A review of available studies suggests higher-dose and adjuvanted flu vaccines are potentially more effective for people 65 and older.
Sources: CDC: Key Facts About Seasonal Flu Vaccine | Influenza (Flu) ↗ · CDC: Flu and People 65 Years and Older | Influenza (Flu) ↗
On vaccines for adults and aging, PubMed lists 1,029 trials in people, 2,989 studies that watched people over time, 153 animal and lab studies. See the counts and searches
Stage 4 because it is recommended in the CDC adult immunization schedule. See the source ↗
A stage shows how far research has got, not whether it will work for you. How stages work
Side effects and risks
- Flu shots may cause soreness, redness or swelling where given, headache, fever, muscle aches, nausea, and tiredness.
- A flu shot can occasionally cause fainting.
- In adults, the nasal spray flu vaccine may cause a runny nose, headache, sore throat, and cough.
- There may be a small increased risk of Guillain-Barré Syndrome, a rare nerve disorder, after a flu vaccine.
- There is a very remote chance of a severe allergic reaction, other serious injury, or death.
Source: CDC: Key Facts About Seasonal Flu Vaccine | Influenza (Flu) ↗
Who should be careful
- People 65 and older should not get the nasal spray flu vaccine.
- The nasal spray flu vaccine is not recommended during pregnancy or for people with certain medical conditions.
- Whether a person can get a given flu vaccine depends on age, health, and allergies to the vaccine or its parts.
Sources: CDC: Flu and People 65 Years and Older | Influenza (Flu) ↗ · CDC: Talking About Influenza Vaccination | Influenza (Flu) ↗ · CDC: Key Facts About Seasonal Flu Vaccine | Influenza (Flu) ↗
Approval and legal status
Different flu vaccines are approved for different age groups. The high-dose flu vaccine is approved for adults 65 and older. The CDC recommends adults get a Tdap or Td booster shot every 10 years.
Sources: CDC: Talking About Influenza Vaccination | Influenza (Flu) ↗ · National Institute on Aging: Vaccinations and Older Adults ↗
Questions to ask your doctor
- Is vaccines for adults a good fit for me, given my health and the medicines I take?
- Is there anything I should avoid or watch for, given my health conditions?
- Where should I start, and how much is right for me?
- How would we tell whether it is helping, and when should we review it?
This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.
What experts say
No expert views collected yet. Each one we add names the person and links to where they said it.
What others are writing
Recent articles about Vaccines for adults from health journalists, hospitals and universities. We link to them; we don't write or endorse them.
New ACC guidance urges uptake of 5 vaccines for heart patients ↗
“Today, the American College of Cardiology (ACC) released vaccination recommendations for adults with cardiovascular disease, urging immunization against COVID-19, influenza, respiratory syncytial virus (RSV), pneumonia, and herpes zoster (shingles).”
The American College of Cardiology recommends adults with heart disease get several vaccines, including COVID-19, flu, RSV, pneumonia, and shingles shots.
Adult immunization schedule updated with new vaccines for 2024 ↗
“The 2024 vaccine schedule for adults includes four new and updated vaccines:”
Harvard Health explains the CDC's 2024 adult vaccine schedule, including updated COVID-19, flu, RSV, and mpox recommendations.
Recent research
Recent studies look at vaccines for older adults
This commentary highlights earlier vaccine studies in an older-adult journal.
A new shingles vaccine trial for adults aged 40 and up
This is a plan for a study that has not started recruiting people yet.
New vaccine study planned for adults aged 65 and older
This trial plans to check whether a new shot is safe and triggers an immune response similar to a current shot.
Comparing a high-dose and standard flu shot in older adults in Singapore
This trial plans to test whether a high-dose flu shot gives stronger antibody levels than a standard shot.
Trials
ClinicalTrials.gov lists 1,383 registered trials that mention Vaccines for adults, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗
The science
Counted from PubMed and ClinicalTrials.gov on Oct 30, 2026, using one search for Vaccines for adults in relation to aging. Each link opens the exact search.
- Randomized trials in people
- 797 search ↗
- Large trials (multicenter or phase 3)
- 246 search ↗
- Phase 3 trials
- 120 search ↗
- Trials in people
- 1,029 search ↗
- Studies that watched people over time
- 2,989 search ↗
- Animal and lab studies
- 153 search ↗
- Registered trials
- 1,383 search ↗
PubMed search used
("zoster vaccine"[tiab] OR "shingles vaccine"[tiab] OR "influenza vaccin*"[tiab] OR "RSV vaccine"[tiab] OR "pneumococcal vaccin*"[tiab]) AND (aging[tiab] OR ageing[tiab] OR longevity[tiab] OR healthspan[tiab] OR "older adults"[tiab] OR "older people"[tiab] OR elderly[tiab] OR "Aged"[mh])
Counts are search results, so they include some records that only mention Vaccines for adults. How we count
Cite or share this page
Longevity Progress. (n.d.). Vaccines for adults: Research stage and evidence. Retrieved October 30, 2026, from https://longevityprogress.com/treatments/adult-vaccines
<iframe src="https://longevityprogress.com/embed/stage/adult-vaccines" title="Vaccines for adults: research stage on Longevity Progress" width="340" height="72" style="border:0" loading="lazy"></iframe>
The badge shows this treatment's current research stage and links back here. It updates by itself when the stage changes.
