What this means
The default therapy for end-stage kidney disease is often dialysis, but for those with advanced age and multimorbidity, it may not provide significant benefit to longevity or quality of life. Conservative management (CM) is a holistic care pathway for those whose care preferences do not align with dialysis.
A plain-English summary is on its way. Until then, this is the start of the authors' own summary.
- Who it was tested in
- Earlier studies
- Kind of research
- A summary of earlier studies
The science
- Original title
- Conservative Management of Kidney Failure.
- Authors
- Yahr J, Schell JO, Gelfand SL
- Journal
- Annual review of medicine
- Published
- Oct 28, 2026
- Study type
- Review
- PMID
- 42950168 ↗
Abstract
The default therapy for end-stage kidney disease is often dialysis, but for those with advanced age and multimorbidity, it may not provide significant benefit to longevity or quality of life. Conservative management (CM) is a holistic care pathway for those whose care preferences do not align with dialysis. CM aims to optimize quality of life over the disease course as patient priorities evolve and their disease progresses. Components of CM include customized chronic kidney disease care, symptom management, and navigation of transitions of care, including end-of-life care. Nephrology clinicians are the central providers of CM and ideally collaborate with a multidisciplinary team to provide medical, psychosocial, and spiritual care.
Yahr J, Schell JO, Gelfand SL Conservative Management of Kidney Failure. Annual review of medicine. 2026. doi:10.1146/annurev-med-042425-022821. PMID: 42950168. https://pubmed.ncbi.nlm.nih.gov/42950168/