What this means
Scientists built a test that finds the drug CJC-1295 in horse blood at very low amounts. The test is meant to help catch illegal use of this drug in racehorses.
Plain-English summary written by an AI model from the abstract. The original is below.
- Who it was tested in
- Blood samples from thoroughbred racehorses given 10 mg of the drug
- Kind of research
- A study
The science
- Original title
- Detection of CJC-1295 in Equine Plasma by ELISA.
- Authors
- Timms M, Cawley A, Steel R
- Journal
- Drug testing and analysis
- Published
- Oct 15, 2026
- Study type
- Study
- PMID
- 42876013 ↗
Abstract
CJC-1295 is a peptide-based drug that stimulates the endogenous production of growth hormone (GH). Compared to other growth hormone releasing hormone (GHRH) analogues, CJC-1295 has an extended half-life due to a drug affinity complex (DAC) that chemically crosslinks the peptide to plasma proteins containing free cysteine residues. As a result, CJC-1295 behaves more like a protein doping agent than a typical peptide-based drug. Using monoclonal antibodies raised against the CJC-1295 peptide, an ELISA was developed for the detection of CJC-1295 protein conjugates in equine plasma at concentrations as low as 12.5 pg/mL. The effectiveness of the assay for controlling the illicit use of CJC-1295 was demonstrated using equine blood samples, obtained from thoroughbred racehorses, following subcutaneous administration of 10 mg of CJC-1295.
Timms M, Cawley A, Steel R Detection of CJC-1295 in Equine Plasma by ELISA. Drug testing and analysis. 2026. doi:10.1002/dta.70171. PMID: 42876013. https://pubmed.ncbi.nlm.nih.gov/42876013/
See all research on CJC-1295 →