Friday, October 30, 2026 · Edition updated 6:00 AM ETFRI, OCT 30 · 6 AM ET editionNext edition in Next --:--:--

Lilly's Duffin reports tirzepatide slowed epigenetic aging clocks in older adults

News report · Lifespan.io · Oct 27, 2026

What happened

Kevin Duffin of Eli Lilly presented data at ARDD on a tirzepatide trial, SURMOUNT-5, in patients aged about 50 to 80 with obesity. He said the 72-week study showed a 1.38-year rise in chronological age, with some epigenetic clocks falling below baseline and pace-of-aging clocks showing a reduction. He also said organ-specific clocks showed biological age decreases in several organs, and he presented only the tirzepatide results.

“I point those out specifically because we saw good clinical endpoints in those disease areas in our clinical trials” — Kevin Duffin

Plain-English summary written by an AI model from the Lifespan.io story; the quote is copied word for word from it.

Read it on Lifespan.io ↗

The original

Headline
ARDD 2026: Traditional Biology to AI-Driven Breakthroughs
From
Lifespan.io (news report)
Published
Oct 27, 2026

One of the oldest and biggest longevity conferences moved this year across the Atlantic, from Copenhagen to Boston. The new location brought ARDD close to several important longevity hubs and might have contributed to this edition’s […]

Report a problem